The fifth exercise of L'Indispensabile uses the same five-note pattern as number 4, but it flips the pairs of notes which creates a significant challenge. The biggest challenge for this one at least in the beginning is more of a mental one, of wrapped the brain around the pattern. Once you become comfortable with the pattern the fourths should be carefully minded.
If you are new to this exercise, then it would be very beneficial to spend a little extra time on the printed version in C major before moving on to the other keys. You may even want to start this one at a slower metronome marking than you were using on number 4 and breaking it down into chunks will also be helpful. Throughout your practice, be sure to keep the tension low.